Striking green walls make an eye-catching backdrop for eclectic art in the London apartment of Fahad Hariri, owner and co–artistic director of Paris design firm Pinto. A portrait by Henry Taylor is mounted above the main salon’s fireplace. Pairs of vintage leopard-print chauffeuses and upholstered folding stools, all by Jansen, join matching custom sofas made using a Colefax and Fowler tartan. The curtains are a Morris & Co. fabric, and the Pinto-designed rug was made by Alfombras Peña.

Steven Gambrel and architect Phillip J. Liederbach craft a bold residence located in a historic Chicago tower, where a Michael Boyd abstraction makes a statement above the custom fireplace surround in the office, which is crowned by a contemporary chandelier from John Salibello. The custom slipper chair is covered in a Fortuny fabric, and the rug is by ALT for Living.

A Jonas Wood painting hangs above the fireplace next to a large work by Laura Owens in the living room of an art-packed Westchester County home designed and decorated by Selldorf Architects. Annabelle Selldorf conceived the sofas, square cocktail tables, and slipper chair, which is paired with a 1950s Seguso table by the fireplace.

In the living room of a fanciful Brussels residence crafted by Madrid-based designer, Lorenzo Castillo, a 1940s Venetian rococo–inspired mirror and early 19th-century Breccia marble mantelpiece are surrounded by Josef Albers artworks and Louis XVI–style consoles that legendary designer Billy Baldwin once used to furnish a Madrid residence.

A Cubist-inspired abstraction by Rodney Graham, mounted on a travertine fireplace surround, presides over the living room of a beach house architect Steven Harris and designer Lucien Rees Roberts conceived for a family in Bridgehampton, New York. A David Weeks Studio sconce hovers next to the customized Francesco Binfaré sofa for Edra. The cocktail table is by Liljencrantz, and the bespoke Moroccan rug was made by Doris Leslie Blau.

Anish Kapoor prints, Hervé Van der Straeten bronze sconces, and minimalist consoles with Lucite legs and stone tops provide a contemporary counterpoint to the living room’s traditional paneling and marble mantelpiece in a Manhattan residence renovated by designer Victoria Hagan in collaboration with Bryan Brown Architects. Hagan designed the sofas, which she grouped with velvet-upholstered Jean Royère chairs around a Carlyle Collective cocktail table and an Alexander Lamont side table.

In the moody lounge inside a century-old San Francisco home remarkably reimagined by Geoffrey De Sousa, Willem Racké Studio applied dark blue-gray lacquer to the paneling, which serves as a backdrop for a Richard Serra artwork above the original limestone fireplace, outfitted with a fire screen by James Bearden for Studio Van den Akker. A Robert Kuo light fixture is mounted above a custom-designed sofa by De Sousa, vintage Milo Baughman swivel chairs, an Yves Klein table, and a silk rug made from recycled saris by J.D. Staron.

A spectacular expanse of book-matched stone surrounds the fireplace in the living room of Cherine Magrabi Tayeb’s Santa Monica home, designed by architect Peter Choate in the early 1980s. Paintings by Richard Prince (left) and Ahmed Alsoudani flank the sitting area outfitted with a Philip and Kelvin LaVerne table and a Warhol-inspired Campbell’s soup can stool by Simon Gavina.

In the living space of an Upper West Side apartment designed by Brian McCarthy, the Hervé Van der Straeten ceiling fixture is a vintage piece from Maison Gerard; the cowhide-upholstered slipper chairs are 1950s French designs from Eric Appel; the cream club chairs are upholstered in a Holly Hunt fabric; and the games table at right is by W. P. Sullivan. A Michael Kovner painting is displayed between the windows, while the fireplace is flanked by works by Lea Nikel, Hannah Ben Dov, and Fima on one side and Jan Rauchwarger on the other.

The living room’s monumental travertine fireplace in an Eddie Lee–designed La Jolla Bungalow showcases a Greek bronze helmet from the fifth century B.C.; a Hans Wegner chair and ottoman, an Eames stool by Herman Miller, and a Phoenix Day floor lamp are grouped on a rug by Patterson Flynn Martin.

In the living area of a Parisian penthouse crafted by Alvise Orsini, a Kehinde Wiley painting pops between Eric Schmitt circular floor lamps. The seating area is furnished with 1950s sea-foam-green chairs, a resin-top table by Hélène de Saint Lager, and a velvet-clad Flexform sofa, all atop a silver-fox rug.

Architect Michael Imber designed this Aspen retreat’s living room around a massive Alexander Calder mobile, while a floating wall was installed to display works by Donald Sultan and Tom Wesselmann from the homeowner’s collection. Milo Baughman rounded-back sofas for Thayer Coggin top a geometric rub by Saddlemans.

In the double-height library of Eugenio López’s Mexico City house, designer Luis Bustamante installed a sculptural Hervé Van der Straeten light fixture.

In the library of supermodel Eugenia Silva’s Madrid home, designed by Casa Muñoz with architectural studio Plantea, a Michael Anastassiades light fixture is suspended above a daybed and custom cocktail table. A painting by Antonio Saura is mounted over the fireplace, which is flanked by an Anacleto Spazzapan wood chair and a Miguel Milá lamp on a pedestal.

In the library of this Charlie Ferrer–designed dwelling in Connecticut, a Mark Steinmetz photograph hangs in the window above a Louis XVI–style desk with a vintage Jean-Pierre Vitrac lamp from Demisch Danant and a Jean Pascaud armchair from Maison Gerard. By the fireplace are a Maynard Monrow text work, a 1947 floor lamp by Angelo Lelli for Arredoluce, a tiger photograph by David Yarrow, and a wing chair upholstered in a Scalamandré velvet.

Deborah Berke Partners and designer Christine van Deusen collaborated on this sumptuous residence on the Upper East Side. A Joan Mitchell abstraction and an Andy Warhol silk-screen painting overlook a seating area that includes a sofa, a bench, and chairs by Achille Salvagni, vintage Jacques Adnet stools, and a bronze cocktail table by Based Upon.

Clarissa Bronfman’s Hamptons home, conjured by Amy Lau, is a lively study of art and objects. Here, installations from Ernesto Neto (top) and Pia Camil (top right) share space with works by Valérie Belin (center) and Laurie Simmons (right), Christopher Chiappa’s Beaded Terrazzo stool, a Brodie Neill chaise longue, and Robert Stadler cocktail tables, commissioned through Carpenters Workshop Gallery.

A painting by Yoshitomo Nara is a focal point in the living room of Manhattan art dealer Marianne Boesky’s Chelsea apartment, designed by architect Deborah Berke.

In the living room of a Tom Kundig–designed masterpiece in Washington state, a screen print by Robert Motherwell is mounted above the fireplace, while a Roche Bobois sofa and dining table are joined by a pair of Charles Pollock armchairs by Knoll. The architect installed a geothermal heating system beneath the concrete floors.

Jacques Grange conceived this Fifth Avenue apartment for major art collector Stacey Bronfman. A Fernando Botero work framed by Agostini sconces preside above a mica fireplace designed by Grange in the living room. Surrounding an Ado Chale table are lounge chairs by Franco Albini and Franco Helg as well as a Grange-designed sofa. Stools by Major Bleu, chairs by Joris Laarman and Royere, and a Jim Zivic table are also included in the space. The carpet was custom made by Beauvais.

In the entry parlor of a Markham Roberts–designed London townhouse, a Guido Mocafico photograph is mounted above the circa-1780 English mantelpiece and a 1950s Piero Fornasetti chair. The Empire armchairs and Arteriors Timber stool (right) stand atop a vintage North African Tuareg mat.