A crumpled-metal sculpture by John Chamberlain presides over Darlene and Jorge M. Pérez’s living room at the top of an OMA-designed building in Coconut Grove. Will Meyer and Gray Davis, the duo who oversaw the interior, grouped sofas and swivel chairs by Minotti with vintage Marco Zanuso lounge chairs around glass-top Amorph tables, arranging everything on a copper-wire rug by Hechizoo. One of Sol LeWitt’s open-cube sculptures stands near the window, which is framed by Donghia fabric curtains.

An early pioneer of Color Field painting, the late artist Kenneth Noland is celebrated for his bold canvases, featuring abstracted forms like targets, chevrons, and stripes. Presiding over the dining area is his 1970 canvas Sea Rise, which illustrates the power of a single hue.

A work by Louise Nevelson overlooks the dining area’s Profiles table and Minotti chairs.

Greeting visitors in the entrance hall is a large Larry Poons painting and a Marisol Escobar sculpture that rests next to a pillar, while a Haas Brothers furry “Beast” stands at the edge of the sitting room just beyond.

“Jorge and Darlene get tickled by these little guys,” says designer Will Meyer of the sheepskin-clad creatures by the Haas Brothers. “They add levity to a serious collection.”

In the office, figures of soccer players by Johannes Mashego Segogela line the bespoke shelves, while a John Wigmore light sculpture is installed over a custom-made KGBL table and Marc Newson chairs; on the far wall, a Helen Frankenthaler canvas hangs above a cabinet by Orfeo Quagliata.

In need of a chic filing cabinet for Jorge’s office, the Meyer Davis team tapped Mexico City–based artisan Orfeo Quagliata to create a custom fused-glass credenza using colors from a vintage rug. Pictured is a similar cabinet he made with Taracea that features his signature barcode pattern.

A multipart Polly Apfelbaum work beckons at the end of a hallway with abstract paintings by Elaine de Kooning (left) and Günther Förg.

Animating the family room are an Ettore Sottsass ceramic sculpture, a Katherine Bernhardt painting of fruit, and an Alex Katz portrait over the TV and a floating shelf by Arthur Casas; a sectional sofa custom made by Louis Interiors wraps around nestling tables by Christian Woo, and an Apparatus light fixture is mounted above an Angelo Mangiarotti table and William Gray chairs.

A sprawling Paul Jenkins canvas occupies a wall in the sitting room, where Forest & Giaconia sofas clad in a Holly Hunt velvet face a modular P. Tendercool table topped by Gaetano Pesce vases and a sculptural platter by Viola Frey; an Elio Monesi floor lamp stands between Vladimir Kagan armchairs, and a Kara Walker wagon sculpture rests on one of the Elan Atelier side tables.

Paintings by Herbert Brandl (left) and Rosa Loy add visual punch to a guest bedroom with a CB2 bed, Arteriors sconces and side tables, and a Stua chair covered in a Maharam fabric designed by artist Sarah Morris.

A vibrant Katherine Bernhardt painting in Darlene and Jorge M. Pérez’s Miami penthouse.

An elegant alabaster and brass lighting pendant by design studio Apparatus adorns the breakfast area. “That room is all about joy, vibrancy, and happiness,” says Meyer.

In the primary bath, lined with Gray Savoie stone, Apparatus lights frame the mirrors, one of which is an artwork by Michelangelo Pistoletto; an Andrianna Shamaris stool perches next to the Stone Forest tub, the sink and tub fittings are by Rohl, the ceramic urn is by Dan Baldwin, and the framed three-part work hanging in the hallway is by Günther Förg.

Painterly marble clads the powder room, which features an Apparatus light and Rohl sink fittings; the artwork reflected in the mirror is by Fernando Botero.

A Joan Mitchell triptych commands one wall of the primary bedroom, which is furnished with a bed custom made by KGBL and dressed in Yves Delorme bedding; Losh Design lamps top the Lawson-Fenning nightstands, and the sofa is by Philippe Malouin for SCP.

A cluster of Verner Panton pendants enlivens the high-contrast kitchen, which includes Wolf ovens, Rohl sink fittings, and glossy cabinetry by Italkraft. Nearby is a 2006 canvas by Dana Schutz.

A wall hanging by Spanish artist Teresa Lanceta (left) and a sensual canvas by Philip Pearlstein are an uncanny match in a guest bedroom.

Offering expansive views of Biscayne Bay, the pool terrace is outfitted with RH chaise longues and a custom-made dining table with chairs by Roda. The small lights mounted to the overhang are by Allied Maker, and the marble sculpture is by Zilia Sánchez.

At the home of Darlene and Jorge M. Pérez in Miami, the terrace, designed by landscape architect Enzo Enea, is furnished with RH sofas, tables by Harbour, and a Prism Hardscapes firepit. Just beyond is a 2020 sculpture by Cuban artist Diango Hernández, whose work has been presented in the Arsenale at the Venice Biennale and in a solo show at Marlborough Contemporary in London.

Pérez Art Museum Miami is one of the city’s leading art institutions. Among the upcoming exhibitions is “Allied with Power,” which spotlights recently acquired works by African and African diaspora artists. It’s on view through February 6, 2022.